Difficult Lesions in the Differential Diagnosis of Endocrine Tumors: Parathyroid Carcinoma
نویسنده
چکیده
Primary hyperparathyroidism (P-HPT) is now recognized as one of the most common of all endocrine disorders. When defined by clinical and pathological parameters, solitary adenomas account for 80-85% of cases of P-HPT, hyperplasias for 10-15% and carcinomas for less than 1% in the US and most Western European countries. However, the incidence of parathyroid carcinoma has been reported to be as high as 5% in Italy and Japan. Whether the relatively high incidence of parathyroid carcinoma in the latter countries is the result of true geographic differences or is related to differing pathological criteria is unknown.
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